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Botany, Traditional Uses, and Pharmacology of Polygonati Rhizoma
Xiao- Jing Chen1, Ju- Feng Duan1, Kai- Qi Liu1, Ying- Ying Guo1, Dong- Peng Wang1, Ming Liu1, Dan Zhao2, Bei Li2, Hong- Liang Li1, Xuan- Bin Wang3
1 Laboratory of Chinese Herbal Pharmacology, Oncology Center, Renmin Hospital, Hubei Key Laboratory of Wudang Local Chinese Medicine Research, School of Pharmacy, Hubei University of Medicine, Shiyan 442000, Hubei, China
2 Biomedical Research Institute, School of Basic Medicine, Hubei University of Medicine, Shiyan 442000, Hubei, China
3 Laboratory of Chinese Herbal Pharmacology, Oncology Center, Renmin Hospital, Hubei Key Laboratory of Wudang Local Chinese Medicine Research, School of Pharmacy, Hubei University of Medicine, Shiyan 442000; Biomedical Research Institute, School of Basic Medicine, Hubei University of Medicine, Shiyan 442000, Hubei, China
Correspondence Address:
Prof. Hong- Liang Li
Laboratory of Chinese Herbal Pharmacology, Oncology Center, Renmin Hospital, Hubei Key Laboratory of Wudang Local Chinese Medicine Research, School of Pharmacy, Hubei University of Medicine, 39 Middle Chaoyang Road, Shiyan 442000, Hubei
China
Prof. Xuan- Bin Wang
Laboratory of Chinese Herbal Pharmacology, Oncology Center, Renmin Hospital, Hubei Key Laboratory of Wudang Local Chinese Medicine Research, School of Pharmacy, Hubei University of Medicine, 39 Middle Chaoyang Road, Shiyan 442000, Hubei, China; Biomedical Research Institute, School of Basic Medicine, Hubei University of Medicine, Shiyan 442000, Hubei Province
China
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/CMAC.CMAC_39_21
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Huang Jing (黄精 Polygonati Rhizoma, PR) was first documented as a herbal medicine in Ming Yi Bie Lu (《名医别录》 Miscellaneous Records of Famous Physicians) in China. However, there was no comprehensive review on the botany, traditional uses, and pharmacological effects of PR till now. In this study, the botany, traditional uses including Taoist medicine, and pharmacological effects of PR were reviewed and summarized to provide insights on drug development of PR. In Taoist medicine, PR maintains agerasia and helps prolong human life-span, and is used for fasting (Bigu). In the Zhong Guo Yao Dian (《中国药典》Chinese Pharmacopeia) version 2020, PR exerts replenishing qi and nourishing yin, invigorating the spleen, moistening the lung, and strengthening the kidney. Pharmacological studies show that PR has effects of anti-oxidation, anti-diabetes, anti-osteoporosis, anti-cancer, anti-hyperlipidemia, cardiomyocyte protection, immunomodulatory, and thus can be used for treatment of infertility, anti-microorganisms, and improving sleep and memory. In conclusion, PR may play a potential role for chronic disease management and health preservation and this very role deserves a more in-depth research.
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